Joaquin Phoenix took home best actor for his portrayal of a tortured loner in Joker while Renee Zellweger won best actress for playing Judy Garland in biopic Judy.
Brad Pitt won best supporting actor for playing an ageing stuntman in Once Upon A Time… In Hollywood and Laura Dern won supporting actress for playing a ruthless divorce lawyer in Marriage Story.
The Irishman stars Robert De Niro and Al Pacino took to the stage together to accept the best acting ensemble gong.
Tarantino also won best screenplay for Once Upon A Time … In Hollywood. Eddie Murphy, who received a lifetime achievement award, was celebrating again when his Dolemite Is My Name won best comedy film.
Elsewhere, Toy Story 4 won best animated feature
In the TV categories, Waller-Bridge won best actress in a comedy series for Fleabag.
Waller-Bridge, who has also won Emmys and Golden Globes for Fleabag‘s lauded second season, described working on the show as “the best experience I’ll probably ever have”.
Waller-Bridge’s co-star Andrew Scott – who plays the Priest – won best supporting actor in a comedy series.
Best drama was won by Succession while best supporting actor in a limited series or movie made for television went to Chernobyl‘s Stellan Skarsgard
Bill Hader won best actor in a comedy series for Barry and Jharrel Jerome took home the award for best actor in a limited series or movie made for television for When They See Us.
The best actress award in a limited series or movie made for television went to Michelle Williams for Fosse/Verdon.
Netflix’s When They See Us was named best limited series ahead of HBO and Sky’s Chernobyl. Show creator Ava DuVernay thanked the streaming giant for letting “a black woman do her thing”.
Regina King won best actress in a drama series for Watchmen, winning ahead of The Crown‘s Olivia Colman and Killing Eve‘s Jodie Comer.
There was more disappointment for British stars in the male category, where Succession‘s Jeremy Strong beat Game Of Thrones‘ Kit Harington and The Crown‘s Tobias Menzies.
King’s Watchmen co-star Jean Smart won best supporting actress in a TV drama while the male equivalent went to Billy Crudup for The Morning Show.
El Camino: A Breaking Bad Movie was named best movie made for TV.
Alex Borstein of The Marvelous Mrs Maisel won best supporting actress in a comedy series.
The prize for best foreign language film was awarded to South Korean dark comedy Parasite and Avengers: Endgame won best action film.